DM-99/199: Alzheimer's disease
Overview
DM-99 has demonstrated the ability to protect and create new neural cells, which are destroyed in neurodegenerative diseases. This dual mechanism of action makes this protein an excellent candidate as a drug for multiple neurological disorders (e.g. Alzheimer’s disease).
DM-99: Protection of Brain Cells
DM-99 has been shown to protect brain cells in a beta amyloid challenge model. Beta amyloid is a protein known to be toxic to brain cells and which many consider to be the hallmark of Alzheimer’s disease.
DM-99 has demonstrated the ability to protect and create new neural cells, which are destroyed in neurodegenerative diseases. This dual mechanism of action makes this protein an excellent candidate as a drug for multiple neurological disorders (e.g. Alzheimer’s disease).
DM-99: Protection of Brain Cells
DM-99 has been shown to protect brain cells in a beta amyloid challenge model. Beta amyloid is a protein known to be toxic to brain cells and which many consider to be the hallmark of Alzheimer’s disease.
DM-99: Creation of New Brain Cells
The Tg2576 mice model overproduces human beta amyloid protein in the brain, which is a protein consistently linked to Alzheimer’s disease. DM-99 treatment resulted in a 38% increase in neurogenesis (new brain cell formation) in the subventicular zone (SVZ), an area of the brain where neurogenesis occurs.
| Symbol | Last | Change |
|---|---|---|
| DMA.V | 0.37 | 0.00 |