Annual report pursuant to Section 13 and 15(d)

Note 3 - Summary of Significant Accounting Policies (Details Textual)

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Note 3 - Summary of Significant Accounting Policies (Details Textual) - USD ($)
 12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Jan. 01, 2019
Research Grant, Recognized, Research Activities Performed 2019 $ 856,000    
Research Grant, Recognized, Research Activities Performed 2018   $ 621,000  
Operating Lease, Liability, Total 159,000    
Operating Lease, Right-of-Use Asset 153,000  
Accounting Standards Update 2016-02 [Member]      
Operating Lease, Liability, Total     $ 205,000
Operating Lease, Right-of-Use Asset     $ 205,000
Research and Development Expense [Member]      
Patent Expense $ 87,000 $ 156,000  
Office Equipment [Member] | Minimum [Member]      
Property, Plant and Equipment, Useful Life 3 years    
Office Equipment [Member] | Maximum [Member]      
Property, Plant and Equipment, Useful Life 10 years    
Computer Equipment [Member]      
Property, Plant and Equipment, Useful Life 4 years