Annual report pursuant to Section 13 and 15(d)

Note 3 - Summary of Significant Accounting Policies - Antidilutive Securities (Details)

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Note 3 - Summary of Significant Accounting Policies - Antidilutive Securities (Details) - shares
12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Antidilutive securities (in shares) 1,468,105 717,431
Employee and Non-employee Stock Options [Member]    
Antidilutive securities (in shares) 639,359 480,035
Common Stock Purchase Warrants [Member]    
Antidilutive securities (in shares) 807,563 216,213
Deferred Share Units [Member]    
Antidilutive securities (in shares) 21,183 21,183