Our lead candidate, DM199, is a potential treatment for several health conditions in which the patient is experiencing low levels of the KLK1 protein.
There is a significant unmet need for effective neurological disease therapies. We are focused on creating a treatment to promote blood flow and to inhibit inflammation and neuronal apoptosis.
According to the National Kidney Foundation, 30 million Americans struggle with chronic kidney disease,1 in 3 adults are at risk for CKD and it is the 9th leading cause of death in the US. CKD , can adversely impact ones quality of life and, potentially lead to end-stage renal disease requiring dialysis or kidney transplant. We are diligently working on a treatment to improve kidney function and avoid further damage and disease progression.
DM199 therapy is intended to restore normal levels of the protein known as tissue kallikrein 1 (KLK1) in patients. The restoration of this protein is intended to allow patients to naturally regulate their blood flow and maintain vascular homeostasis as well as reduce inflammation and oxidative stress.
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